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Levothyroxine should be taken on an empty stomach, at least 30-60 minutes before breakfast and at least 4 hours apart from other medications that may interfere with absorption
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Data from a sub-study of the STEP 1 clinical trial indicates that approximately 40% of the weight lost on semaglutide can be lean mass (muscle and bone) without targeted interventions (Wilding et al., 2021)
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